Royal Air Force Typhoon FGR4s have operated alongside French warplanes in a combined operation against an hidden munitions depot in Syria used by the IS group, per a report from the British defence ministry.
The site, located using surveillance, was thought to be storing arms and explosives, the statement said, and was positioned in hills just to the north of the historic site of Palmyra in Syria's central region.
"Our fighter planes used precision-guided Paveway IV munitions to hit a series of approach shafts leading to the site... preliminary assessments suggest the strike was effective," the MoD said.
There was no sign of any civilian casualties in the attack on Saturday evening and every plane involved made a safe return, the ministry further stated.
The British jets were supported by a Voyager tanker plane.
Daesh - alternatively referred to as the so-called Islamic State - established jihadist rule over significant areas in Syria and Iraq before its territorial defeat in 2019.
"This operation shows our UK leadership, and commitment to work closely with allied nations, to eradicate any re-emergence of the terrorist group and their violent and radical beliefs in the region," Britain's Defence Chief the Defence Secretary remarked.
UK warplanes have performed surveillance missions over Syria to "deter any attempted comeback" of the group following its defeat at the battle of Baghuz in 2019, the authorities noted.
"I extend gratitude to all the members of British forces participating in this operation for their professionalism and their bravery," Healey commented. "Including them were thousands of British personnel deployed over Christmas and New Year. This operation, to remove militants who endanger our safety, shows how UK forces are ready to step up, continuously, keeping Britain secure domestically and influential overseas."
During December, the American forces executed what it termed a "massive strike" targeting Islamic State objectives in the country, subsequent to an attack killed two US troops and a civilian linguist in the Palmyra area.
The UN reports IS still boasts roughly 5-7 thousand combatants in Iraq and Syria.